Gallery
PM Modi visit USA
Only the mirror in my washroom and phone gallery see the crazy me : Sara Khan
Karnataka rain fury: Photos of flooded streets, uprooted trees
Cannes 2022: Deepika Padukone stuns at the French Riviera in Sabyasachi outfit
Ranbir Kapoor And Alia Bhatt's Wedding Pics - Sealed With A Kiss
Oscars 2022: Every Academy Award Winner
Shane Warne (1969-2022): Australian cricket legend's life in pictures
Photos: What Russia's invasion of Ukraine looks like on the ground
Lata Mangeshkar (1929-2022): A pictorial tribute to the 'Nightingale of India'
PM Modi unveils 216-feet tall Statue of Equality in Hyderabad (PHOTOS)
India Open Competition in Shotgun, organised by the National Rifle Association of India (N
- Hockey India names Amir Ali-led 20-man team for Junior Asia Cup
- Harmanpreet Singh named FIH Player of the Year, PR Sreejesh gets best goalkeeper award
- World Boxing medallist Gaurav Bidhuri to flag off 'Delhi Against Drugs' movement on Nov 17
- U23 World Wrestling Championship: Chirag Chikkara wins gold as India end campaign with nine medals
- FIFA president Infantino confirms at least 9 African teams for the 2026 World Cup
US FDA approves 1st oral pill by Pfizer to treat Covid Last Updated : 23 Dec 2021 10:45:49 AM IST 
As Omicron variant spreads globally, the US Food and Drug Administration (FDA) has issued an emergency use authorisation (EUA) for the Pfizer antiviral pill to treat Covid-19 along with caution for people with certain pre-existing conditions -- heralding a new era for the future, over-the-counter treatment of the deadly respiratory disease that has killed millions.
Pfizer's Paxlovid (nirmatrelvir tablets and ritonavir tablets, co-packaged for oral use) has been approved for the treatment of mild-to-moderate coronavirus disease (Covid-19) in adults and paediatric patients (12 years of age and older weighing at least 40 kg) with positive results of direct SARS-CoV-2 testing.The pill has also been approved for those at high risk for progression to severe Covid-19, including hospitalisation or death.Paxlovid is available by prescription only and should be initiated as soon as possible after diagnosis of Covid-19 and within five days of symptom onset, the FDA said in a statement late on Wednesday."The authorisation introduces the first treatment for Covid-19 that is in the form of a pill that is taken orally -- a major step forward in the fight against this global pandemic," said Patrizia Cavazzoni, director of the FDA's Center for Drug Evaluation and Research."This authorisation provides a new tool to combat Covid-19 at a crucial time in the pandemic as new variants emerge and promises to make antiviral treatment more accessible to patients who are at high risk for progression to severe Covid-19," Cavazzoni added.Paxlovid is not authorised for the pre-exposure or post-exposure prevention of Covid or for initiation of treatment in those requiring hospitalisation due to severe or critical Covid-19.The pill is also not a substitute for vaccination in individuals for whom Covid-19 vaccination and a booster dose are recommended.Paxlovid consists of nirmatrelvir, which inhibits a SARS-CoV-2 protein to stop the virus from replicating, and ritonavir, which slows down nirmatrelvir's breakdown to help it remain in the body for a longer period at higher concentrations.Paxlovid is administered as three tablets (two tablets of nirmatrelvir and one tablet of ritonavir) taken together orally twice daily for five days, for a total of 30 tablets.The pill is not authorised for use for longer than five consecutive days.The primary data supporting this EUA for Paxlovid are from EPIC-HR, a randomised, placebo-controlled clinical trial studying Paxlovid for the treatment of non-hospitalised symptomatic adults with a laboratory confirmed diagnosis of SARS-CoV-2 infection.Patients were adults 18 years of age and older with a prespecified risk factor for progression to severe disease or were 60 years and older regardless of prespecified chronic medical conditions."Possible side-effects of Paxlovid include impaired sense of taste, diarrhoea, high blood pressure and muscle aches. Using Paxlovid at the same time as certain other drugs may result in potentially significant drug interactions," the FDA said.Using Paxlovid in people with uncontrolled or undiagnosed HIV-1 infection may lead to HIV-1 drug resistance."Ritonavir may cause liver damage, so caution should be exercised when giving Paxlovid to patients with pre-existing liver diseases, liver enzyme abnormalities or liver inflammation," the FDA warned.IANS Washington For Latest Updates Please-
Join us on
Follow us on
What binds the two most talked about nations - India and Pakistan together? What makes the
Bollywood star Ranveer Singh and filmmaker Aditya Dhar seeked divine blessings at the Gold
LG Electronics Inc said on Wednesday that it will introduce new C with its artificial inte
172.31.16.186
